New york: The main indices on Wall Street exchange closed lower Thursday. According to Qatar News Agency, the S and P 500 fell 37.78 points, or 0.50 percent, to 7,534.62. The Nasdaq Composite dropped 383.76 points, or 1.47 percent, to 25,885.47. The Dow Jones Industrial Average declined 109.13 points, or 0.21 percent, to 52,549.51.