Doha: Scientists from the University of Oxford in the UK have discovered that the natural compound spermidine, present in certain foods, can enhance the immune response to vaccines in some elderly individuals.According to Qatar News Agency, researchers noted that the immune system gradually diminishes in effectiveness with age, a process termed immune senescence. Consequently, older adults often exhibit reduced efficacy in their response to vaccines and produce fewer antibodies. This prompted scientists to investigate whether spermidine, a compound found in foods such as lentils, chickpeas, broccoli, mushrooms, and certain cheeses, could bolster immune system function.The research revealed that spermidine can mitigate signs of immune system aging and trigger a natural cellular self-cleaning process. This process aids in the removal of damaged components and sustains cellular health and activity. The study involved 40 healthy volunteers over the age of 65, all of whom had previously received three doses of the COVID-19 vaccine. Participants were divided, with some receiving daily spermidine supplements over a 13-week span, while others were given a placebo.Approximately a quarter of the participants demonstrated a very weak immune response to the vaccine, even after three doses, with signs of accelerated aging observed in their immune cells. However, post-spermidine supplementation, there was an improvement in both antibody levels against the coronavirus and B cell function. This enhancement bolstered the immune system's capacity to neutralize various strains of the virus.